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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Pediatr Blood Cancer. 2010 Sep;55(3):546–549. doi: 10.1002/pbc.22573

Figure 1.

Figure 1

SBDS protein expression in the bone marrow. A. Immunohistochemical staining for SBDS in a representative control BM biopsy (100X). B. Immunohistochemical staining for SBDS in a BM biopsy from a representative patient with SDS (100x). In both A and B, open arrow: megakaryocyte; closed arrow: neutrophil precursor; asterick: osteoblast; black circle: neutrophil. C. Mean SBDS immunohistochemical staining scored on a scale of 0 (weak) to 3 (strong). Grey boxes denote individual patient scores. Colored boxes represent multiple specimens from the same patient. Asterisk denotes the SDS patient without a confirmed mutation in SBDS. The mean immunohistochemical score for each diagnostic group is indicated by the black box and the 95% confidence interval is shown with the vertical bar.