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. Author manuscript; available in PMC: 2010 Aug 2.
Published in final edited form as: J Biomol Screen. 2009 Jul 29;14(7):853–858. doi: 10.1177/1087057109340314

Table 1.

Senescence-inducing compounds identified by high throughput screening. (+) and (−) are indicative of presence and lack of anti-proliferative activity, respectively, as reported previously in PubChem and in the literature.

Compound Name AZQ Bithionol Dichlorophene Pyrithione
Structure graphic file with name nihms197270t1.jpg graphic file with name nihms197270t2.jpg graphic file with name nihms197270t3.jpg graphic file with name nihms197270t4.jpg
PubChem ID 42616 2406 3037 1570
PubChem Anti-Cancer Activity In Vitro + + + +
In Vivo − − − Not Reported
Mechanism of Action DNA Alkylation Unknown Unknown Zn2+ Ionophore