Figure 8.

AFM images of (A) unphosphorylated PKR and (C) phosphorylated PKR. Images are 1 μm × 1 μm with a height scale of 2 nm. In (A), different molecular conformations can be found. Examples of these are shown enlarged in (B): almost entirely extended conformation (1), shapes with three resolvable segments (2), shapes showing only two resolved segments and a broader linking region (3), and molecules in which the individual segments are very close together (4). The scale bar in (B1) is 20 nm. Height scale of all images is 2 nm as indicated next to image (C).