Fig. 5.

Effect of in vivo treatment of 5A-POC on cholesterol efflux by plasma. apoE-KO mice (n = 6) were injected intravenously with 5A-POPC (30 mg/kg), and pooled plasma collected at baseline (black bars) and 1 h (white bars), 6 h (gray bars), and 24 h (striped bars) after injection were tested for cholesterol efflux from control mock-transfected cells, ABCA1-transfected cells, or ABCG1-transfected cells. Results represent the mean ± 1 S.D. of quadruplicates. ∗, p < 0.05 compared with baseline result.