Fig. 7.
Effect of 5A-POPC treatment on in vivo cholesterol efflux from macrophages. C57BL/6 mice (n = 7) were injected intraperitoneally with RAW 264.7 macrophage radiolabeled with 3H-cholesterol. 5A-POPC (30 mg/kg) was injected intraperitoneally 8 h before and within 1 h before cell injection. Twenty-four hours after cell injection, plasma was monitored for radioactive counts (A), and stool was monitored for fecal sterols (B) and fecal bile acids (C). Results represent the mean ± 1 S.D. of seven replicates. ∗, p < 0.01 compared with the untreated control group.