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Glucose and insulin homeostasis in Ephx2(+/+) and Ephx2(−/−) mice treated with STZ. IGTT in STZ-induced diabetic mice. After a 6-h fast, mice received i.p. injections of 1 g/kg glucose (time = 0). Blood glucose (A) and insulin (B) were measured before and at varying time points after glucose administration. The following mice were used: STZ-Ephx2(+/+) mice (n = 4) and STZ-Ephx2(−/−) mice (n = 4). ∗, P < 0.05 versus STZ-Ephx2(+/+).
