Table 1.

Patient Characteristics

Sex (male/female)	16/10
Age, median (range)	59 years (22–76)
ECOG performance status 0/1	11/15
Stage (regional disease confined to neck/metastatic)	7/19
Prior therapy/no prior therapy	24/2
Combined modality therapy (n = 16)
Surgery + radiation + chemotherapy	9
Radiation + chemotherapy	4
Surgery + radiation	3
Chemotherapy exposure (n = 13)
Paclitaxel-based: single patient each with paclitaxel alone; paclitaxel +doxorubicin; paclitaxel + cisplatin; paclitaxel + doxorubicin + cisplatin	4
Doxorubicin-based: doxorubicin alone (six patients) and doxorubicin + cisplatin (2)	8
Cisplatin single agent	1
Single modality therapy (n = 8)
Surgery	7
Radiation	1
Participating centers–patient enrollment:
Cleveland	20
Detroit	4
Pittsburgh	2

ECOG, Eastern Cooperative Oncology Group.