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. Author manuscript; available in PMC: 2010 Aug 2.
Published in final edited form as: Brain Res. 1975 Nov 21;98(3):517–527. doi: 10.1016/0006-8993(75)90370-4

TABLE V. EFFECT OF VARIOUS MONOAMINE OXIDASE INHIBITORS ON THE ACTIONS OF 5,7-DHT.

Values represent the mean ± S.E.M. of 5–14 determinations. Animals were pretreated with monoamine oxidase inhibitors 30 min before receiving 200 µg of 5,7-DHT intracisternally and were killed 21 days after treatment.

Treatment Dose
mg/kg		 Brain monoamine content (ng/g)
5-HT NE DA
Saline + 5,7-DHT — 130 ± 10* 229 ± 16* 601 ± 40
Iproniazid + 5,7-DHT 100 161 ± 12* 352 ± 34 683 ± 73
Pheniprazine + 5,7-DHT 15 170 ± 30* 414 ± 25 676 ± 81
Tranylcypromine + 5,7-DHT 10 132 ± 10* 402 ± 22 625 ± 59
(Saline) control — 402 ± 12 358 ± 21 677 ± 28
Pheniprazine + Saline 15 500 ± 40 388 ± 35 625 ± 52
*

P < 0.001 when compared with control.