Figure 1.
IL-1 inhibits ZBP-89 mRNA expression in HGF. HGF cultures were serum-deprived for 16 hours prior to addition of IL-1β (10 ng/ml) and/or IL-4 (10 ng/ml). Total RNA was harvested 12 hours after cytokine treatment, quantitated by real-time PCR and normalized to levels of GAPDH.
Notes: The graph represents data from seven independent experiments performed in triplicate, expressed as mean ± SEM. Statistical significance was determined using student’s t-test. **p < 0.01.
Abbreviations: GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HGF, human gingival fibroblasts; IL, interleukin; PCR, polymerase chain reaction; SEM, standard error of mean.
