Figure 4.
ZBP-89 mRNA is inhibited by IL-1β and LPS, but not by TNF-α in WI-38 cells. WI-38 cell cultures were serum-deprived for 16 hours prior to addition of cytokines/inflammatory mediator (10 ng/ml). Total RNA was harvested 12 hours after treatment, quantitated by real-time PCR, and normalized to levels of GAPDH.
Notes: The graph represents data from two independent experiments performed in triplicate, expressed as mean ± SEM.
Abbreviations: GAPDH, glyceraldehyde-3-phosphate dehydrogenase; EGF, epidermal growth factor; IL, interleukin; LPS, lipopolysaccharide; PCR, polymerase chain reaction; TNF, tumor necrosis factor; SEM, standard error of mean.
