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. Author manuscript; available in PMC: 2010 Aug 2.
Published in final edited form as: J Pharmacol Exp Ther. 1976 Mar;196(3):594–604.

TABLE 2. Effects of TRH on ethanol-induced sleep and hypothermia in various species.

All animals received TRH (10 mg/kg i.p.) simultaneous with ethanol. Rectal temperatures were determined in rats and hamsters 40 minutes, in guinea pigs 60 minutes, and in gerbils 30 minutes after TRH injection

Animal Ethanol
Dose
N Sleeping Time
Rectal Temperature
Saline TRH Saline TRH
g/kg min ± S.E.M. ° C ± S.E.M.
Rat 3.5 16 89.3 ± 5.81 59.2 ± 8.74a 37.1 ± 0.13 36.9 ± 0.24
Guinea pig 3 7 139.3 ± 6.94 14.0 ± 1.22b 36.4 ± 0.30 36.9 ± 0.29
Hamster 4 9 158.6 ± 8.69 108.7 ± 5.95b 36.1 ± 0.18 37.5 ± 0.09b
Gerbil 3.8 18 224.9 ± 25.0 78.4 ± 8.39b 36.5 ± 0.39 38.5 ± 0.24b

When compared with saline:

a

P < .02.

b

P < .01.