Table 2.
Descriptive information for pedigree subjects.
| Mean ADI domain scores (SD; N) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Diagnostic group | N | Male: female | IQ > 70 (%) | Mean age (SD) | Mean SRS score (SD; N; % child version) | Social | Verbal | Non-verbal |
Restr/ Repet |
| Autism* | 135 | 119:16 (7.44:1) | 69/125 (55.2) | 13.87 (11.44) | 107.0 (31.4; N = 126; 75.4%) | 21.8 (6.4) | 17.2 (4.7) | 12.3 (2.3; N = 26) | 6.7 (2.6) |
| ASD† | 46 | 36:10 (3.60:1) | 37/43 (86.1) | 16.98 (15.25) | 86.4 (29.1; N = 41; 75.6%) | 12.7 (5.9) | 10.5 (6.4) | (N = 0) | 5.3 (2.9) |
| All affected subjects | 181 | 155:26 (5.96:1) | 106/168 (63.1) | 14.64 (12.51) | 101.9 (33.5; N = 167; 75.5%) | 19.5 (7.5) | 15.2 (6.1) | 12.3 (2.3; N = 26) | 6.3 (2.7) |
| All relatives with no ASD diagnosis | 448 | 211:237(0.9:1) | 37.30 (20.49) | 28.7 (24.0; N = 351; 22.5%) | |||||
* 11 cases were missing an Autism Diagnostic Interview (ADI); five cases were missing an Autism Diagnostic Observation Schedule.
† Three cases were missing an ADI; no cases were missing an ADOS.
SD, standard deviation; SRS, Social Responsiveness Scale; Restr/Repet, Restricted Interests/Repetitive Behaviors Domain Score