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. 2010 May 25;1:9. doi: 10.1186/2040-2392-1-9

Table 6.

Power analysis referring to a family-based design for rare variants with high penetrance and a dominant model.

Allele frequency Penetrance Power

AA AB BB
0.10 0.8 0.8 0.0 1.000

0.08 0.8 0.8 0.0 1.000

0.06 0.8 0.8 0.0 1.000

0.04 0.8 0.8 0.0 0.986

0.02 0.8 0.8 0.0 0.642

0.01 0.8 0.8 0.0 0.075

0.10 0.9 0.9 0.0 1.000

0.08 0.9 0.9 0.0 1.000

0.06 0.9 0.9 0.0 1.000

0.04 0.9 0.9 0.0 0.998

0.02 0.9 0.9 0.0 0.767

0.01 0.9 0.9 0.0 0.144

0.10 1.0 1.0 0.0 1.000

0.08 1.0 1.0 0.0 1.000

0.06 1.0 1.0 0.0 1.000

0.04 1.0 1.0 0.0 0.999

0.02 1.0 1.0 0.0 0.751

0.01 1.0 1.0 0.0 0.146