Table 1.
GSEA of human stem cell signatures
| Gene Set Name (N)1 | Number of enriched genes | NES | FDR q-val |
|---|---|---|---|
| ES EXP1 (315) | 128 | 2.16 | <0.0001* |
| ES EXP2 (32) | 9 | 1.89 | <0.0001* |
| MYC Targets2 (664) | 182 | 1.63 | 0.0022* |
| SOX2 Targets (584) | 166 | 1.54 | 0.0058* |
| MYC Targets1 (199) | 55 | 1.47 | 0.013* |
| NANOG Targets (797) | 225 | 1.38 | 0.021* |
| OCT4 Targets (242) | 63 | 1.22 | 0.068 |
| NOS Targets (152) | 32 | 1.08 | 0.23 |
| H3K27 BOUND (886) | 245 | -1.65 | 0.0026* |
| PRC2 Targets (508) | 126 | -1.59 | 0.0038* |
| EED Targets (800) | 183 | -1.55 | 0.0042* |
| SUZ12 Targets (819) | 201 | -1.65 | 0.005* |
| NOS TFS (32) | 5 | -1.08 | 0.24 |
1 N: number of genes from each gene set in mouse chip.
NES: normalized enrichment score.
NES > 0: enrichment in tumors; NES < 0: enrichment in normal skin.
*Significant enrichment.