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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Neuroscience. 2010 May 24;169(3):1414–1420. doi: 10.1016/j.neuroscience.2010.05.042

Fig. 6. Modulation of reflex-related changes in firing by improgan.

Fig. 6

Effect of icv injection of saline (Sal) and improgan (Imp) on the OFF-cell pause (A) and ON-cell burst (B). Pause index: firing rate at time of the reflex (or at mean pre-drug reflex latency for trials when tail flick was inhibited following improgan) as percent of firing immediately prior to heat onset. A pause index of 100 would indicate no reflex- or heat-related slowing. Burst: firing rate in spikes/s at time of reflex (or at mean pre-drug reflex latency if no flick). ***p < 0.001 compared to pre-drug baseline period, t-test for correlated means (pause index); ** p < 0.01 compared to pre-drug baseline period, Wilcoxon's signed ranks test (ON-cell burst). Same OFF- and ON-cells as in Fig. 4.