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. Author manuscript; available in PMC: 2011 Aug 15.
Published in final edited form as: Dev Biol. 2010 Jun 19;344(2):992–1000. doi: 10.1016/j.ydbio.2010.06.016

Figure 5. P granules and PIE-1 localize normally in pam-1 mutants in which dhc-1 is inactivated.

Figure 5

In wild-type embryos, germline P granules and PIE-1 protein localized to the cytoplasm at the posterior pole prior to the first cell division. Localization of these determinants failed in pam-1 mutants. Inactivation of dhc-1 on its own did not affect the normal localization of P granules or PIE-1. When dhc-1 was inactivated in pam-1 mutants, both P granules and PIE-1 localized as in wild-type, providing further evidence that polarity was restored in the pam-1; dhc-1(RNAi) embryos. Pseudocleavage is marked by arrows. Embryos are approximately 50μm in length.