Table 1.
Demographic and illness factors.
| Nonpatient Comparisons (NC) | Bipolar Mania (BD) | Schizophrenia (all SCZ) | Paranoid SCZ (pSCZ) | Non-paranoid SCZ (npSCZ) | Difference | |
|---|---|---|---|---|---|---|
| Age | 28.8 (9.5) | 31.6 (13.6) | 36.4 (12.0) | 39.5 (10.8) | 31.7 (13.2) | ns |
| Gender | 12 M, 14 F | 9 M, 8 F | 10 M, 8 F | 6 M, 5 F | 4 M, 3 F | ns |
| Years of education | 14.9 (1.7) | 13.5 (2.4) | 13.2 (2.3) | 12.5 (1.5) | 14.3 (2.9) | NC > BD and pSCZ (p<.03) |
| Age of onset of Illness | -- | 23.6 (9.5) | 25.4 (8.7) | 27.5 (8.9) | 22.1 (7.8) | ns |
| Years of illness duration | -- | 8.1 (7.3) | 10.6 (8.0) | 11.7 (8.4) | 8.9 (7.5) | ns |
| Number of days in treatment | -- | 2.4 (1.8) | 5.6 (10.2) | 7.5 (12.9) | 2.7 (1.7) | ns |
| Illness subtype | -- | Current Episode Manic | 11 paranoid, 2 disorganized, 5 undifferentiated | 11 paranoid | 2 disorg., 5 undiff. | -- |
| YMRS total score | -- | 27.3 (9.8) | 18.4 (7.6) | 17.0 (7.7) | 20.7 (7.3) | BD > all SCZ and pSCZ (p<.01) |
| BPRS total score | -- | 38.1 (14.5) | 36.2 (7.8) | 37.5 (9.0) | 34.2 (5.5) | ns |
| Risperidone dose (mg) | -- | n = 8 3.3 (2.1) |
n = 11 4.0 (1.2) |
n = 6 3.2 (1.6) |
n = 5 4.9 (1.0) |
ns |
| Valproate dose (mg) | -- | n = 6 1833.3 (516.4) |
n = 2 2250.0 (353.6) |
n = 1 2500.0 |
n = 1 2000.0 |
ns |
| Lithium Dose (mg) | -- | n = 5 1180.0 (563.0) |
-- | -- |
Note: For all cases except gender and illness subtype, values in the first five columns represent means and standard deviations. YMRS= Young Mania Rating Scale, BPRS = Brief Psychiatric Rating Scale