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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Mol Pharm. 2010 Aug 2;7(4):1342–1347. doi: 10.1021/mp100036b

Figure 2.

Figure 2

Uptake of pramipexole into hOCT2-HEK and mock cells. A, Pramipexole uptake was greater into hOCT1-MDCK cells than into mock cells. B, Apparent permeability of pramipexole versus concentration is plotted for pramipexole uptake into hOCT2-HEK cells and mock cells. Also plotted is the apparent permeability of TEA at 71.3 μM into hOCT2-HEK cells and mock cells. C, Inhibition of pramipexole uptake (5 μM) into hOCT2-HEK and mock cells by 10 μM corticosterone. ***, p < 0.001, compared with hOCT2-HEK cells not treated with corticosterone. Error bars denote SEM.