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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Mol Pharm. 2010 Aug 2;7(4):1342–1347. doi: 10.1021/mp100036b

Figure 3.

Figure 3

Uptake of pramipexole into hOCT3-HEK and mock cells. A, Pramipexole uptake was greater into hOCT3-HEK cells than into mock cells. B, Apparent permeability of pramipexole versus concentration is plotted for pramipexole uptake into hOCT3-HEK cells and mock cells. Also plotted is the apparent permeability of TEA at 71.3 μM into hOCT3-HEK cells and mock cells. C, Inhibition of pramipexole uptake (10 μM) into hOCT3-HEK and mock cells by 100 or 200 μM corticosterone. ***, p < 0.001, compared with hOCT3-HEK cells not treated with corticosterone. Error bars denote SEM.