Figure 1.
Peripheral inflammation activates spinal Rheb, S6 kinase, S6 and 4E-BP1. Bar graphs display % change from naïve control (t = 0h) for Rheb (A), phoshpo (p)-S6 kinase (B), p-S6 (C) and p-4E-BP1 (D) in the spinal cord at different time points following carrageenan-induced inflammation. Representative Western blots of p-S6K, p-S6 and p-4E-BP1 are shown below each bar graph. Data are reported as mean ± SEM, n = 4. * represents p < 0.05 compared to naïve control.