FIG. 9.

Alterations of supra-threshold neural responses in furosemide-treated ears. Mean CAP I/O functions obtained with 2, 4, 8, and 16 kHz probe tones from control ears (n = 5) and ears treated with furosemide for 7 days (n = 11). Error bars are SEM values. Note that I/O functions from furosemide-treated gerbils have shifted thresholds and are flattened at all test frequencies. Because these animals were young with no hair cell and ganglion cell pathologies, it is most probably the reduced EP that is causing these shifts.