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The M. tuberculosis usp mutants exhibited no survival defect in response to a range of stress conditions. A number of other stress conditions were also tested (see Table 1), but no survival phenotype was observed when comparing the usp mutants to the wildtype H37Rv. As examples, the results for A) low pH and B) Nitrosative stress (5 mM GSNO) are shown. Error bars represent the standard deviations of 3 independent cultures.
