Table 10.

Other interventions (5)

Author	Cancer Dx	Cancer Tx	Study type	Time of assessment	Final N/intervention 1	Final N/intervention 2
Rojas de Morales et al. 2001 [55]	Hematologic malignancies (defined)	Not provided	RCTc	All were seen pre-treatment then assessed twice a week during hospitalization, once a week if outpatient; seen until CTd completed and hematological parameters reestablished	N = 5	N = 7
			Blinding unknown	154 evaluations	Preventive protocol	Oral physiotherapy
				Average evaluations per patient: 13 (2–30)	Reinforce oral physiotherapy, removal of plaque, non-alcoholic 0.05% fluoride mouth rinse, topical application of 20% miconazole during chemotherapy, use of toothpaste 4 times a day before and after chemotherapy, toothpaste substituted with sodium bicarbonate during chemotherapy
Rudat et al. 2000 [56]	Squamous cell carcinoma	RTb	Cohort	Before and 1 year post-RTb	N = 17	N = 18
					Intravenous Amifostine (200 mg/m2)	Nothing
Sela et al. 2000 [58]	H&Na	Not provided (RTb assumed)	N-RCS	Post-RTb	Honey from wildflowers, swish 5 ml for 5 min and swallow
				Assessment before and after rinse (same visit)	N = 12 radiated patients	N = 12 healthy controls
Sela et al. 1994 [57]	H&Na	RTb	N-RCS	Post-RTb	Appliance with etched (in vitro exposure to cola for 60 min) enamel slabs (extracted human molars), for radiated and non-radiated patients
					N = 14 (8 RT, 6 non-RT)	N = 14 (8 RT, 6 non-RT)
					Chew on a piece 20 g hard cheese for 5 min	Chewing parafilm
Toljanic et al. 1999 [41]	Hematologic malignancies (defined) and breast cancer	CTd: 46	Cohort	Pre-cancer treatment then daily exam during treatment	N = 48
		CTd and RTb: 2			Minimal intervention pretherapy dental treatment

^aHead and neck

^bRadiation

^cRandomized control trial

^dChemotherapy