Table 2.

Summary data on Vitamin D and Asthma and/or Recurrent Wheeze

Investigator	Population Studied	Results	Reference
Black et al.	>14,000 adults using the NHANES database	↑FEV1 and ↑FVC in subjects whose vitamin D level was in the highest quintile	48
Brehm et al.	Asthmatic children from Costa Rica	Log10 ↑ in vitamin D level associated with ↓hospitalizations, ↓antiinflammatory medication, and ↓markers of allergy	49
Camargo et al.	Mother-child pre-birth cohort	Mothers in highest quartile of vitamin D intake had lower risk for child at age 3 with recurrent wheeze	23
Devereux et al.	Mother-child pre-birth cohort	Mothers in highest quintile of vitamin D intake had lower risk for child at age 5 to have ever wheezed, wheezing in the previous year, and persistent wheezing. No association of vitamin D levels with asthma, spirometry, or atopic sensitization.	50
Gale et al.	Mother-child pre-birth cohort	Maternal 25(OH)D concentrations above 30 ng/mL associated with an ↑risk of eczema at 9 months and ↑risk of asthma at 9 years	51