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. Author manuscript; available in PMC: 2010 Oct 22.
Published in final edited form as: Nature. 2010 Apr 4;464(7292):1196–1200. doi: 10.1038/nature08889

Figure 2. AA5x angiogenesis requires klf2a.

Figure 2

a, Embryos subjected to whole mount in situ hybridization at 65 hpf using indicated riboprobes (klf2a, cdh5). Lateral view, anterior to the left, dorsal is up. Embryos were injected with 2 ng of scrambled control (left) or tnnt2 (right) MO. Aortic arch region is denoted by black boxes; aortic arches 4-6 are indicated by numbered arrows in cases where staining is present. b, Microangiogram of 72 hpf Tg(kdrl:egfp)la116 embryo injected with 11 ng-embryo scrambled control MO (top) or klf2a ATG MO (bottom); arrowheads indicate position of normal AA5x formation, arrows denote lateral dorsal aortae. Dorsal views, anterior is up.