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Loss of PACAP does not alter entrainment or free-running rhythms. Representative double-plotted behavioral actograms of C57Bl/6 WT (n=37) and PACAP-null (n=38) mice demonstrate that entrainment to 12-h light:12-h dark cycles and free-running rhythms are not affected by the lack of PACAP. Shaded area represents darkness. PACAP +/+ (WT), PACAP −/− (PACAP-null).
