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. Author manuscript; available in PMC: 2010 Aug 3.
Published in final edited form as: J Nat Prod. 2004 Dec;67(12):2063–2069. doi: 10.1021/np040140c

Figure 3.

Figure 3

Compound 1 regulates nuclear HIF-1α protein availability in T47D cells. Western blot results of nuclear extract samples for HIF-1α and HIF-1β proteins following 4 h treatment with 1 (100 μM) under normoxic or hypoxic (1% O2) conditions (A). Results from quantitative real time RT-PCR analysis of HIF-1α mRNA levels (B). Compound treatment and data processing of the real time RT-PCR studies are the same as that described in Figure 2A.