Skip to main content
Applied and Environmental Microbiology logoLink to Applied and Environmental Microbiology
. 1980 May;39(5):957–961. doi: 10.1128/aem.39.5.957-961.1980

Mouse bioassay for Fusarium metabolites: rejection or acceptance when dissolved in drinking water.

H R Burmeister, R F Vesonder, W F Kwolek
PMCID: PMC291458  PMID: 7396486

Abstract

Ten metabolites of Fusarium species (butenolide, diacetoxyscirpenol, equisetin, fusaric acid, gibberellic acid, moniliformin, NRRL 6227 peptide, T-2 toxin, vomitoxin, and zearalenone) were added to the drinking water of mice to determine whether they were consumed or refused. Of the 10, only the trichothecenes--diacetoxyscirpenol, T-2 toxin, and vomitoxin--were refused. Refusal of 2 mg of the trichothecenes per liter was not enhanced by adding 100 mg of zearalenone per liter.

Full text

PDF
957

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Burmeister H. R., Bennett G. A., Vesonder R. F., Hesseltine C. W. Antibiotic produced by Fusarium equiseti NRRL 5537. Antimicrob Agents Chemother. 1974 Jun;5(6):634–639. doi: 10.1128/aac.5.6.634. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Burmeister H. R., Ciegler A., Vesonder R. F. Moniliformin, a metabolite of Fusarium moniliforme NRRL 6322: purification and toxicity. Appl Environ Microbiol. 1979 Jan;37(1):11–13. doi: 10.1128/aem.37.1.11-13.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Burmeister H. R. T-2 toxin production by Fusarium tricinctum on solid substrate. Appl Microbiol. 1971 Apr;21(4):739–742. doi: 10.1128/am.21.4.739-742.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Burmeister H. R., Vesonder R. F., Hesseltine C. W. Swelling of Penicillium digitatum conidia by a Fusarium acuminatum NRRL 6227 metabolite. Mycopathologia. 1977 Nov 30;62(1):53–56. doi: 10.1007/BF00491996. [DOI] [PubMed] [Google Scholar]
  5. Forsyth D. M., Yoshizawa T., Morooka N., Tuite J. Emetic and refusal activity of deoxynivalenol to swine. Appl Environ Microbiol. 1977 Nov;34(5):547–552. doi: 10.1128/aem.34.5.547-552.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Grove M. D., Yates S. G., Tallent W. H., Ellis J. J., Wolff I. A., Kosuri N. R., Nichols R. E. Mycotoxins produced by Fusarium tricinctum as possible causes of cattle disease. J Agric Food Chem. 1970 Jul-Aug;18(4):734–736. doi: 10.1021/jf60170a037. [DOI] [PubMed] [Google Scholar]
  7. Hsu I. C., Smalley E. B., Strong F. M., Ribelin W. E. Identification of T-2 toxin in moldy corn associated with a lethal toxicosis in dairy cattle. Appl Microbiol. 1972 Nov;24(5):684–690. doi: 10.1128/am.24.5.684-690.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Kotsonis F. N., Smalley E. B., Ellison R. A., Gale C. M. Feed refusal factors in pure cultures of Fusarium roseum 'graminearum'. Appl Microbiol. 1975 Sep;30(3):362–368. doi: 10.1128/am.30.3.362-368.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Mirocha C. J., Pathre S. V., Behrens J. Substances interfering with the gas-liquid chromatographic determination of T-2 mycotoxin. J Assoc Off Anal Chem. 1976 Jan;59(1):221–223. [PubMed] [Google Scholar]
  10. Mirocha C. J., Pathre S. V., Schauerhamer B., Christensen C. M. Natural occurrence of Fusarium toxins in feedstuff. Appl Environ Microbiol. 1976 Oct;32(4):553–556. doi: 10.1128/aem.32.4.553-556.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Vesonder R. F., Ciegler A., Burmeister H. R., Jensen A. H. Acceptance by swine and rats of corn amended with trichothecenes. Appl Environ Microbiol. 1979 Aug;38(2):344–346. doi: 10.1128/aem.38.2.344-346.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Vesonder R. F., Ciegler A., Jensen A. H. Isolation of the emetic principle from Fusarium-infected corn. Appl Microbiol. 1973 Dec;26(6):1008–1010. doi: 10.1128/am.26.6.1008-1010.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Vesonder R. F., Ciegler A., Jensen A. H., Rohwedder W. K., Weisleder D. Co-identity of the refusal and emetic principle from Fusarium-infected corn. Appl Environ Microbiol. 1976 Feb;31(2):280–285. doi: 10.1128/aem.31.2.280-285.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Vesonder R. F., Ciegler A., Rogers R. F., Burbridge K. A., Bothast R. J., Jensen A. H. Survey of 1977 crop year preharvest corn for vomitoxin. Appl Environ Microbiol. 1978 Dec;36(6):885–888. doi: 10.1128/aem.36.6.885-888.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Applied and Environmental Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES