Figure 7.
Na+ channel blockers inhibit subthreshold voltage-gated conductance and the action potentials evoked by simulated and synaptic GABA-PSPs. (A, B) Example traces of simGABA-PSPs evoked by injection of GABA-PSC waveform in control conditions (upper traces) and in the presence of 1 μM TTX (A) and 200 μM phenytoin (B) (bottom traces). (C) Synaptic GABA-PSPs in control conditions (upper traces) and in the presence of 100 μM phenytoin (bottom traces).