Figure 9.

Effect of partial blockade of NKCC1 on GDPs. (A) Photograph of the recording setup and extracellular GDP recordings in control conditions (left traces) and in the presence of 0.3 μM bumetanide (right traces). (B) Normalized GDPs width, frequency, and propagation rate in the presence of 0.3 μM bumetanide. (C, D) Cross-correlograms of unitary APs (C) and GDPs (D) between two distinct CA regions (CA3 and CA1, or within CA3) in control conditions (black) and in the presence of bumetanide (red). Dashed lines show SEM. (B–D) Pooled data from four slices.