Table 1.
Group activations for pain (noxious heat)>warmth (non-noxious heat) contrast
| Region of activation | Broadmann | Coordinates |
Z score | Volume (mm3) | ||
|---|---|---|---|---|---|---|
| X | Y | Z | ||||
| Medial frontal gyrus | 6 | 0 | −12 | 68 | 2.97 | 224 |
| Middle frontal gyrus | R46/45 | 44 | 32 | 24 | 3.73 | 1144 |
| Middle frontal gyrus | R6 | 54 | 4 | 52 | 3.37 | 608 |
| Inferior frontal gyrus | R9 | 48 | 8 | 36 | 3.55 | 1160 |
| Inferior frontal gyrus | R10 | 38 | 42 | 2 | 3.48 | 328 |
| Anterior cingulate gyrus* | 24 | 6 | 8 | 36 | 3.36 | 184 |
| Posterior cingulate gyrus* | 23 | −2 | −28 | 34 | 3.47 | 424 |
| Insula/claustrum* | R13 | 28 | 16 | 0 | 4.30 | 2568 |
| Insula* | R13 | 42 | 0 | 10 | 2.94 | 248 |
| Insula* | R13 | 38 | −22 | 12 | 2.92 | 208 |
| Insula/Inferior Parietal | R13 | 44 | −32 | 26 | 3.93 | 360 |
| Superior temporal gyrus | L22 | −70 | 2 | 2 | 3.15 | 312 |
| Superior temporal gyrus | R41/42 | 54 | −38 | 12 | 3.21 | 160 |
| Inferior parietal lobe | R40 | 54 | −36 | 32 | 2.99 | 200 |
| Inferior parietal lobe | R40 | 66 | −46 | 40 | 3.16 | 168 |
| Inferior parietal lobe | L39 | −42 | −68 | 40 | 3.42 | 344 |
| Putamen/caudate | L | −20 | 0 | 14 | 3.45 | 240 |
| Thalamus (anterior)* | L | −8 | −2 | 6 | 3.42 | 192 |
| Thalamas (ventral anterior)* | R | 16 | −6 | 14 | 3.55 | 528 |
R and L hemisphere is not designated for maxima within 6 mm of midline. Coordinates are in MNI space.
Designates regions selected for correlations with ASI and FPQ scores in Table 3.