Skip to main content
. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: J Immunol. 2010 Mar 3;184(7):3768–3779. doi: 10.4049/jimmunol.0903151

FIGURE 2.

FIGURE 2

rhIL-7 prevents sepsis-induced apoptosis of T cells. Sham or septic mice were treated with 5 μg of rhIL-7 at 90 min after surgery. Spleens were harvested 24 h later, and apoptosis was determined by the TUNEL method. rhIL-7 prevented the marked increase in CD4 and CD8 T cell apoptosis occurring during sepsis. *Sham versus CLP is significantly different at p < 0.05; p value shown in the figure compares CLP versus CLP + IL-7. (n = 6–8 mice per group in the two sham groups, and n = 11 mice per group in the two CLP groups; results from three combined studies.)