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IL-7R expression is increased in sepsis. Sham or septic mice were treated with 5 μg of rhIL-7 for three consecutive days and killed on the third postoperative day. Sepsis induced a marked increase in IL-7R expression in CD4 and CD8 T cells. Treatment with rhIL-7 caused a decrease in IL-7R expression in sham and septic mice (n = 4 mice for each of the four groups; one independent study). *p < 0.05; **p < 0.01; ***p < 0.001 compared to sham mice.
