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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Infect Dis Clin North Am. 2010 Sep;24(3):693–703. doi: 10.1016/j.idc.2010.04.012

Table 1.

The association between smoking and the relative risk of latent tuberculosis infection, progression to active disease and mortality from active TB.

Meta-analyses: pooled relative risks (95%C.I)
Slama et al. 2007(6) Lin et al. 2007(7) Bates et al. 2007(8)
TB outcome TB infection ~1.8 (1.5–2.1) 1.7 – 2.2 (1.5–2.8) ~1.7 (1.5–2.0)
TB disease ~2.3 (1.8–3.0) ~2.0 (1.6–2.6) ~2.3 (2.0–2.8)
TB mortality ~2.2 (1.3–3.7) ~2.0 (1.1–3.5) ~2.1 (1.4–3.4)

Adapted from van Zyl-Smit RN, Pai M, Yew WW, Leung CC, Zumla A, Bateman ED, et al. Global Lung Health: The Colliding Epidemics of Tuberculosis, Tobacco Smoking, HIV and COPD. Eur Respir J. 2010; 35: 27–33