Table 2.
Adenosine tolerance and hemodynamic effects.
| Control | Case | |||||
|---|---|---|---|---|---|---|
| Parameter | Study 1 | Study 2 | p | Study 1 | Study 2 | p |
| Rest | ||||||
| Heart rate, beats/min | 60 ± 7 | 67 ± 10 | 0.411 | 59 ± 9 | 61 ± 12 | 0.317 |
| Systolic BP, mmHg | 130 ± 13 | 130 ± 11 | 0.912 | 138 ± 25 | 139 ± 25 | 0.874 |
| Diastolic BP, mmHg | 81 ± 16 | 82 ± 12 | 0.787 | 82 ± 11 | 70 ± 9 | 0.004 |
| Peak stress | ||||||
| Heart rate, beats/min | 82 ± 16 | 83 ± 10 | 0.883 | 76 ± 19 | 70 ± 12 | 0.063 |
| Systolic BP, mmHg | 131 ± 12 | 129 ± 12 | 0.537 | 130 ± 31 | 135 ± 20 | 0.671 |
| Diastolic BP, mmHg | 82 ± 16 | 83 ± 10 | 0.134 | 71 ± 14 | 71 ± 15 | 1.000 |
| Adenosine infusion | ||||||
| Duration, min | 2.3 ± 0.6 | 2.2 ± 0.7 | 0.583 | 1.7 ± 0.5 | 1.7 ± 0.6 | 0.204 |
| Chest pain | 4 (40) | 4 (40) | 0.133 | 5 (50) | 4 (40) | 0.524 |
| Breathlessness | 4 (40) | 1 (10) | 0.400 | 5 (50) | 5 (50) | 0.206 |
| Flushing, headache, dizziness | 8 (80) | 8 (80) | 0.467 | 3 (30) | 3 (30) | 0.183 |
Values are number (%) or mean ± SD. BP = blood pressure.