Table 1.

Measurements included in the DiaDDZoB Study

Variable	Categories	Measurement occasion
Demographic factors
Age		M0
Gender	Male, female	M0
Ethnicity	Dutch, other Caucasian (white Western) groups, other (Asian, black, Turkish/Moroccan)	M0
Marital status	Married/living together, single, LAT relationship, divorced/ separated, widowed	M0, M1, M2
Living situation	Independent, residing with family/friends, residing in a nursing home	M0, M1, M2
Employment status	Paid employment, umemployed, disabled, no paid employment, retired	M0, M1, M2
Education level	Primary school, primary vocational education, secondary school, secondary vocational education, higher vocational education, university	M0
Medical history
Disease duration	Months/years since diabetes diagnosis	M0, M1
Medical history	M0: lifetime history: arterial disease, bypass/angioplasty, myocardial infarction, stroke, angina pectoris, high cholesterol, kidney disease, asthma/COPD, cancer, rheumatic disorder, depression, burn-out M1 and M2: during last 12 months: arterial disease, bypass/angioplasty, myocardial infarction, stroke, angina pectoris, high cholesterol, asthma/COPD, osteoporosis, depression, kidney disease	M0, M1, M2
Treatment
Current hyperglycemia treatment modality	None, diet, diet/oral agents, diet/ insulin, diet/oral agents/insulin, other	M0, M1, M2
Medication use	ACE inhibitors, β-blockers, calcium antagonists, diuretics, other antihypertensive agents, statins	M0, M1, M2
Laboratory tests
HbA1c		M0, M1, M2
Fasting glucose		M0, M1, M2
Cholesterol	Total cholesterol	M0, M1, M2
	LDL-cholesterol	M0, M1, M2
	HDL-cholesterol	M0, M1, M2
	Triglycerides	M0, M1, M2
Protein levels	Albumin	M0, M1, M2
	Creatinin	M0, M1, M2
	Albumin-to-creatinin ratio	M0, M1, M2
	MDRD clearance	M1, M2
Physical examination
Length	Length in metres	M0, M1, M2
Weight	Weight in kilograms	M0, M1, M2
Body Mass Index (BMI)	Weight in kilograms/(length in metres)2
Blood pressure	Systolic	M0, M1, M2
	Diastolic	M0, M1, M2
Fundus photography	Unassessable, normal, retinopathy	M0, M1, M2
Foot examination	M0: Normal, abnormal M1 and M2: Normal, neuropathy, ischemia, wound/ulcer, excessive coldness	M0, M1, M2
Lifestyle indicators
Smoking behavior	Current smoking: yes/no, number of cigarettes per day	M0, M1, M2
	Additional for M0: smoking history
Alcohol consumption	Current alcohol consumption: yes/no, number of consumptions per week	M0, M1, M2
	Additional for M0: history of alcohol consumption
Physical activity	Hours per week of active physical activity	M0, M1, M2
	Hours per week of sportive physical activity	M0, M1, M2
Psychological factors
Depressive symptoms	Edinburgh Depression Scale (EDS)	M0, M1, M2
Type D personality	Type D Scale-14 (DS14)	M1, M2
Social support	O'Hara's modified Social Support Scale	M0, M1, M2
Loneliness	Single item concerning feelings of loneliness in the past 12 months	M0, M1, M2
Stressful life events	Single item concerning stressful life event(s) in the past 12 months	M0, M1, M2