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| S100A7 | Sensitivity | Specificity | PPV | AUC |
| Nuclear Staining | ||||
| Normal vs. squamous cell hyperplasia | 34.5 | 95.0 | 88.9 | 0.664 |
| Normal vs. dysplasia | 44.0 | 95.0 | 81.5 | 0.691 |
| Normal vs. HNSCC | 67.0 | 95.0 | 93.1 | 0.824 |
| Cytoplasmic Staining | ||||
| Normal vs. squamous cell hyperplasia | 54.3 | 84.0 | 79.8 | 0.650 |
| Normal vs. dysplasia | 68.0 | 84.0 | 68.0 | 0.746 |
| Normal vs. HNSCC | 74.0 | 84.0 | 82.2 | 0.788 |
