Table 1.
Demographics of the 162 Children
Characteristics | Total N = 162 |
Immune Reconstitution Inflammatory Syndrome |
P-value | |
---|---|---|---|---|
Yes n = 62 |
No n = 100 |
|||
Sex Female Male |
93 (57.4) 69 (42.6) |
29 (31) 33 (48) |
64 (69) 36 (52) |
0.023 |
Age 6 – 12 months 13 – 59 months 5 – 12 years 12 – 18 years |
16 (9.9) 57 (35.2) 56 (34.6) 33 (20.4) |
3 (4.8) 21 (37) 26 (46) 12 (36) |
13(81) 36(63) 30(54) 21(64) |
0.24 |
Scheduled visit Yes No |
113 (69.8) 49 (30.2) |
40(35) 22(45) |
73(65) 27(55) |
0.17 |
Duration on ART 2 weeks – < 1 month 1 month – < 3 months 3 months – 6 months |
51 (31.7) 25 (14.9) 86 (53.4) |
28(55) 10(40) 24(28) |
23(45) 15(60) 62(72) |
0.007 |
Weight for age* < −2 SD below normal ≥ −2 SD below normal |
57 (37) 97 (63) |
21(37) 38(39) |
36(63) 59(61) |
0.46 |
†Type of ART NNRTI based Regimen PI based Regimen Triple NRTI Regimen |
147 (90.7) 9 (5.6) 6 (3.7) |
53(36) 6(67) 3 (50) |
94(64) 3(33) 3(50) |
0.16 |
CD4+%, Pre-ART* ≤ 15% > 15% |
112 (70.4) 47 (29.6) |
49(44) 12(25) |
63(56) 35(75) |
0.033 |
WHO Clinical stage, Pre-ART I / II III / IV |
44 (27.2) 118 (72.8) |
15(34) 47(40) |
29(66) 71(60) |
0.31 |
NNRTI = non-nucleoside reverse transcriptase inhibitors, PI = Protease Inhibitor, NRTI = Nucleoside reverse transcriptase inhibitors.
Six children were not assessed for nutritional status, and three were not assessed for the CD4+ levels