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Examples of guanine–ribose interactions: the original G-ribo interaction with GN2–O4′ and GO2′–O2′ H-bonds (A); “reverse G-ribo” interaction with GN2–O2′ and GO2′–O4′ H-bonds (B); a variant G-ribo with three H-bonds, GN2–O3′, GN3–O2′, and GO2′–O2′ (C). All examples are from 23S rRNA, PDB 1VQ8.
