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. 2010 Apr 26;588(Pt 13):2351–2360. doi: 10.1113/jphysiol.2010.187054

Figure 5. GAD blockade by mercaptopropionic acid (MPA) does not change the sensitivity of eIPSCs to exogenous GABA when both GAT-1 and GAT-2/3 are blocked.

Figure 5

A–C, statistical data showing the effects of SNAP-5114 (40 μm) plus NO-711 (10 μm) and different GABA concentrations applied in thepresence of SNAP-5114 plus NO-711 on the mean eIPSC amplitude (A), PPR (B) and failure rates (C) at P2–3 (open symbols) and P5–7 (filled symbols). Each point represents a mean value obtained in at least five experiments. MPA (100 μm) waspresent in the extracellular saline throughout the experiments. Dashed lines show the control values taken from the experiments with SNAP-5114 plus NO-711 and SNAP-5114.