Table 4.
Physiological impact of acute inspiratory pressure loading
| Healthy control %Δ | Heart failure %Δ | P value | |
|---|---|---|---|
| Pulmonary pressures | |||
| Wb | 209.9 ± 43.2 | 208.6 ± 23.4 | 0.13 |
| Ppl mean insp | 98.1 ± 14.0 | 89.7 ± 7.8 | 0.62 |
| ∫Ppl,inspt | 219.7 ± 39.5 | 183.0 ± 12.7 | 0.44 |
| ∫Ppl,totalt | 304.5 ± 74.9 | 333.0 ± 72.4 | 0.79 |
| Haemodynamics | |||
 |
9.8 ± 2.3 | 2.1 ± 5.3 | 0.20 |
| SV | 7.9 ± 2.4 | −2.1 ± 6.0 | 0.14 |
| HR | 1.8 ± 0.5 | 4.6 ± 2.2 | 0.23 |
| SBP | 4.3 ± 1.3 | 4.0 ± 1.1 | 0.88 |
| DBP | −0.3 ± 3.3 | 0.2 ± 2.1 | 0.91 |
| MAP | 4.6 ± 1.2 | 2.5 ± 1.2 | 0.25 |
| LBF | 0.3 ± 6.0 | −5.4 ± 6.0 | 0.26 |
 |
−7.9 ± 5.5 | −4.3 ± 7.8 | 0.36 |
 |
−0.8 ± 5.7 | −6.2 ± 5.7 | 0.24 |
| LVR | 6.7 ± 9.1 | 17.6 ± 11.3 | 0.24 |
| Blood gases | |||
 |
−7.9 ± 1.3 | −3.2 ± 1.8 | 0.05 |
 |
7.1 ± 1.6 | 1.9 ± 1.8 | 0.06 |
 |
−0.7 ± 0.6 | −2.0 ± 0.6 | 0.35 |
 |
1.6 ± 1.0 | −6.9 ± 2.2 | 0.004 |
 |
3.0 ± 0.9 | 4.4 ± 1.8 | 0.50 |
 |
1.3 ± 2.5 | −8.8 ± 3.2 | 0.02 |
| a–v O2 diff | −1.0 ± 0.8 | 0.1 ± 1.5 | 0.56 |
| Ventilation | |||
 |
8.4 ± 2.7 | 3.7 ± 6.3 | 0.52 |
 |
−9.1 ± 4.2 | −2.8 ± 5.9 | 0.40 |
| VT | 3.8 ± 7.7 | 15.1 ± 8.1 | 0.33 |
| RR | −9.3 ± 6.7 | −12.9 ± 4.3 | 0.65 |
| TI | 37.0 ± 12.2 | 36.8 ± 11.6 | 0.99 |
| TTOT | 7.6 ± 6.8 | 15.1 ± 7.7 | 0.47 |
Symbols and abbreviations as defined in Table 3. Data are presented as mean ±s.e.m.