Table 1.
Baseline Study | Tx Wk 11 (Saline Study) | Tx Wk 12 (Naloxone Study) | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Age | BMI | PM | E2 | FSH | %sleep | Hf | E2 | FSH | %Slep | Hf | E2 | FSH | %Sleep | Hf |
1 | 57 | 20.5 | 7 | 20 | 87 | --- | --- | 17 | 60 | 83.8% | 3 | 15 | 73 | 83.9% | 1 |
2 | 53 | 22.5 | 4 | 10 | 70 | 77.2% | 2 | 10 | 76 | 77.3% | 4 | 11 | 79 | 81.1% | 4 |
3 | 51 | 29.0 | 1 | 22 | 61 | --- | --- | 17 | 53 | --- | --- | --- | --- | --- | |
4 | 47 | 24.9 | 7 | 17 | 65 | 88% | 6 | 14 | 63 | 81.6% | 7 | 17 | 68 | 83.0% | 3 |
5 | 55 | 23.2 | 2 | 12 | 79 | 87.6% | 5 | 12 | 79 | 83.6% | 8 | 17 | 87 | 84.6% | 5 |
6 | 53 | 30.0 | 4 | 12 | 61 | 72.4% | 8 | 23 | 60 | 78.2% | 9 | 16 | 66 | 71.6% | 3 |
7 | 54 | 24.7 | 1.5 | 14 | 60 | 80.9% | 10 | 12 | 59 | 70.7% | 9 | 18 | 56 | 87.9% | 6 |
PM = postmenopausal; E2= pg/ml; FSH = mIU/ml; hormone values determined from the 1pm blood sample. Hf = hot flash events recorded on actigraph; % sleep = percent of time spent sleeping during 11pm-7am calculated from actigraph data; unavailable for subject 3 and subject 1 (baseline).