Average BDI scores across study conditions during test compound administration (varenicline and placebo). BDI scores were recorded in the mornings after each dose of both varenicline and placebo study conditions, and were averaged across both study conditions and participants.
Notes: Bars represent mean of eight participants and 64 measurements for placebo, 63 for varenicline. Unidirectional brackets indicate one standard deviation.
Abbreviation: BDI, Beck’s Depression Inventory.