TABLE 1.
ATPase activity of FMDV deletion and active site mutants
| Construct | ATPase activity | Source/Reference |
|---|---|---|
| pmol Pi/pmol protein/min | ||
| GST-FMDV 2C | 17 | This report |
| GST-PV 2C | 13.3a | Ref. 23 |
| GST-MNV p41 | 17.3a | Ref. 58 |
| FMDV 2C(34–318) | 2.3 | This report |
| FMDV 2C(34–318) K116A (Walker A) | 0.017 | This report |
| FMDV 2C(34–318) D160A (Walker B) | 0.017 | This report |
| FMDV 2C(34–318) N207A (Motif C) | 0.042 | This report |
| FMDV 2C(61–318) | 0.46 | This report |
a The values reported in the associated references were converted to these units for comparison.