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Islet apoptosis in AdTRα-infected mice following vehicle or STZ administration. STZ was administered to AdLacZ and AdTRα pre-infected mice, after which mice were euthanized 5 days later for histological assessment of islet apoptosis using a TUNEL assay. The number of apoptotic cells normalized to the relative islet area is shown. Approximately 30 islets were assessed, in which a minimum of 10 slides were analyzed per mouse. All data are expressed as mean ± S.D. *, p < 0.05.
