Table 4. Overrepresented Functions among Epididymis-Specialized, Secreted Genes.
| Function (GO term) | Number of Genes Observeda | Number of Genes Expectedb | Pc |
|---|---|---|---|
| Biological process | |||
| Defense response (0006952) | 26 | 10.3 | <0.03 |
| Response to bacterium (0009617)d | 10 | 1.4 | <0.01 |
| Lipid metabolism (0006629) | 36 | 14.5 | <10−3 |
| Cell adhesion (0007155) | 38 | 13.7 | <10−4 |
| Signaling (0007167) | 22 | 6.7 | <0.01 |
| Molecular function | |||
| Peptidase activity (0008233) | 33 | 15.1 | <0.05 |
| Transferase activity (0016757)d | 23 | 5.4 | <10−5 |
| Structural (0005201) | 10 | 1.9 | <0.04 |
| Phospholipid binding (0005543)d | 20 | 5.5 | <0.01 |
| Enzyme inhibition (0004857)d | 17 | 5.0 | <0.03 |
a
The number of epididymis-specialized, secreted genes that are associated with a function.
b
The number of genes expected to have that function, based on the genome.
c
The Bonferroni-corrected probability of observing this deviation by chance alone.
d
This term has additional daughter terms which are significantly overrepresented (supplementary fig. 1, Supplementary Material online).