Table 3.

Considerations for choosing viral load strategy to detect virologic failure.

Factors	Costs	Clinical considerations
Assay type and level of detection	Cost per assay	Accuracy
Inherent error of assay type	Cost per assay	Accuracy
Laboratory space to avoid contamination during processing	Space cost	Quality assurance
Personnel availability	Personnel cost	Turnaround time
Personnel training	Personnel cost	Quality assurance
Clinic population size	Cost per pool	Turnaround time
Rate of virologic failure	Cost per pool	Accuracy
Rate of screening	Cost per pool	Accuracy and turnaround time