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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: J Child Psychol Psychiatry. 2009 Dec 11;51(7):827–837. doi: 10.1111/j.1469-7610.2009.02201.x

Figure 4. Reward cue-elicited peak signal change in nucleus accumbens VOI.

Figure 4

Trial-type-averaged time series data were extracted from a mask custom-drawn for each subject in the nucleus accumbens (NAcc; center). Peak anticipatory signal occurred 6 s after cue presentation. NAcc recruitment increased with incentive magnitude in both controls (upper-most graphs), and in adolescents with externalizing disorders (AED; lower graphs). Analysis of variance across all trial magnitudes indicated that signal change did not significantly differ between trials when the subject did (solid bars) or did not (empty bars) hit the target (ANOVA p = .97). There were no main or interactive effects of subject group on reward-anticipatory NAcc signal change. ** denotes p <.05 per simple-effect two-tailed paired t-test.