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(a) The thermal melting profile of poly(dT) · poly(dA)xpoly(dT) triplex (-•-) and its complex with berberine at alkaloid/DNA ratio of 0.1 (-O-) and 0.3 (-▲-). (b) Circular dichroic spectrum (1) of the same triplex (48.8 μM) with increasing concentrations up to (31.05 μM) of berberine (9). Reprinted in part from Das et al. [48] with permission from 2003 Adenine Press.
