Table 1.
Control minus experimental postlesion p < 0.005
| +/− | Cluster region | Volume (in mm3) | Cluster hemisphere | Peak location region | Peak t value (postlesion) | Peak location relative to anterior commissure (in mm) |
||
|---|---|---|---|---|---|---|---|---|
| x | y | z | ||||||
| + | Entorhinal cortex | 28 | L | Rostral entorhinal cortex | 15.32 | −7.5 | −0.625 | −14.375 |
| + | Postcentral gyrus | 9 | R | Area 3 | 14.44 | 25 | 1.875 | 4.375 |
| + | Bed nucleus of stria terminalis region | 8 | L | Bed nucleus of stria terminalis | 7.17 | −4.375 | 1.25 | −0.625 |
| − | Parietal | 81 | R | Parietal area PG | 16.75 | 13.125 | −23.75 | 18.125 |
| − | ACC | 43 | Midline | Areas 6/32 and 23c | 13.69 | −0.625 | −5.625 | 15.625 |
| − | Motor | 12 | R | Area 4 | 29.28 | 6.875 | −3.125 | 21.25 |
| − | White matter near OFC | 11 | R | 10.52 | 11.875 | 9.375 | 5.625 | |
| − | Motor | 10 | R | Area 6 | 8.74 | 13.75 | −0.625 | 18.75 |
Regions where we observed a significant interaction (p < 0.05, two-tailed uncorrected) and where control animals showed greater metabolism than OFC-lesioned animals at time 2 (after lesion; p < 0.005, two-tailed uncorrected). Regions are presented with the direction of the correlation, brain regions involved, volume, and hemisphere of cluster. We also report the local maxima for each statistical cluster with its corresponding t value and location (in millimeters relative to the anterior commissure). Note that our analyses did not include areas >20 mm posterior to the anterior commissure or areas anterior to the genu of the corpus callosum (see Materials and Methods for details).